Indications:
Piperazine is an anthelmintic effective against round-worm (Ascaris) and tread-worm (Enterobius) and has no significant effect on hookworm, tape-worm and whipworm. Since activity of the worm is not stimulated, there is little danger of blockage of the intestines or the bile duct, even in heavily infected patients. Piperazine affects all stages of parasites in the gut but appears to have little or no effect on larvae in the tissues.
Composition:
Each 5 ml contains:
Piperazine Citrate equivalent to 750 mgPiperazine Hydrate.
Spirit of Chloroform 0.05 ml.
Dosage:
Treatment for Threadworm Infections
For adult and children aged over 12 years, a daily in divided dose, equivalent to 2gm of piperazine hydrate is given by mouth for 7 days.
For children:
7 - 12 years of age: 10ml of syrup daily in divided doses, for 7 days.
4 - 6 years of age: 5 - 7 ml of syrup daily doses , for 7 days.
2 -3 years of age: 5ml of syrup daily doses , for 7 days.
9 - 24 months: 2.5ml of syrup daily doses , for 7 days.
A second course after 7 days interval may be required.
Treatment of Round-worm Infections
Usual adult oral dose, the equivalent of 4mg of piperazine hydrate as a single dose with the evening meal.
For children:
Up to 2 years of age: 5 ml of syrup as single dose with the evening meal.
2 - 8 years of age: 1 5 ml of syrup as single dose with the evening meal.
9 - 12 years of age: 20 ml of the syrup as single dose with the evening meal.
If the patient is constipated, a purgative should be given on the morning after the dose of anthelmintic so that the worms are expelled before the effect of the drug wears off.
Manufactured in Singapore.
